While glycogen synthase A deficiency can reduce the growth and proliferation of Chlamydia
muridarum, the effect of glycogen synthase A on the pathogenic process of C. muridarum
remains unclear. To characterize the effect of glycogen synthase A deficiency on the
pathogenicity of C. muridarum in the genital tract, BALB/c mice were intravaginally
inoculated with wild-type, plasmid-free and glycogen synthase A-deficient C. muridarum,
and the genital tract tissue was isolated to assess the severity of hydrosalpinx and the levels …